THE UNIVERSITY OF BRITISH COLUMBIA DEPARTMENT OF STATISTICS TECHNICAL REPORT #252 Bayesian inference of gene-environment interaction from incomplete data: What happens when information on environment is disjoint from data on gene and disease?
نویسندگان
چکیده
منابع مشابه
Marginal Analysis of A Population-Based Genetic Association Study of Quantitative Traits with Incomplete Longitudinal Data
A common study to investigate gene-environment interaction is designed to be longitudinal and population-based. Data arising from longitudinal association studies often contain missing responses. Naive analysis without taking missingness into account may produce invalid inference, especially when the missing data mechanism depends on the response process. To address this issue in the ana...
متن کاملتحلیل برآورد اثر متقابل ژن ـ محیط در بیماران مبتلا به سرطان پستان
Background and objectives: There is growing interest in assessing gene-environment interaction in the course of case-control studies. Difficulties related to the sampling of controls have led to the development of a range of non-traditional methods that do not require controls for estimating gene-environment interaction. One of these new modalities is the case-only approach, in which the asse...
متن کاملAccurate Inference for the Mean of the Poisson-Exponential Distribution
Although the random sum distribution has been well-studied in probability theory, inference for the mean of such distribution is very limited in the literature. In this paper, two approaches are proposed to obtain inference for the mean of the Poisson-Exponential distribution. Both proposed approaches require the log-likelihood function of the Poisson-Exponential distribution, but the exact for...
متن کاملComparison of three types of G × E performance plot for showing and interpreting genotypes’ stability and adaptability
A G × E performance (interaction, profile) plot for showing genotype-by-environment data is discussed. Three versions of such a plot are compared: the regular performance plot; the performance plot based on coded data (environment-centered performance plot), in which the environment means of a trait are subtracted from data; and the performance plot based on data standardized in environments (e...
متن کاملExtending the Qualitative Trajectory Calculus Based on the Concept of Accessibility of Moving Objects in the Paths
Qualitative spatial representation and reasoning are among the important capabilities in intelligent geospatial information system development. Although a large contribution to the study of moving objects has been attributed to the quantitative use and analysis of data, such calculations are ineffective when there is little inaccurate data on position and geometry or when explicitly explaining ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2009